BPC-157 (Body Protection Compound-157) is a synthetic peptide consisting of 15 amino acids. It’s derived from a naturally occurring protective protein found in the stomach lining called Body Protection Compound (BPC).
The synthetic version (BPC-157) is designed to mimic and enhance the regenerative and protective effects of the natural compound.
When encapsulated, BPC-157 is taken orally in capsule form rather than injected, typically as a dietary supplement or research compound.
Mechanism of Action
BPC-157 acts as a bioregulatory peptide, promoting tissue repair, reducing inflammation, and supporting gut health. It interacts with several biological pathways:
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Angiogenesis Stimulation
- Increases the formation of new blood vessels by upregulating VEGF (vascular endothelial growth factor).
- This enhances blood flow and nutrient delivery to damaged tissues.
- Fibroblast Activation
- Stimulates fibroblasts to produce collagen, aiding in tendon, ligament, and muscle repair.
- Stimulates fibroblasts to produce collagen, aiding in tendon, ligament, and muscle repair.
- NO Pathway Regulation
- Modulates the nitric oxide (NO) pathway, improving circulation and protecting endothelial cells.
- Modulates the nitric oxide (NO) pathway, improving circulation and protecting endothelial cells.
- Gastrointestinal Repair
- Protects and heals the gut mucosa, likely by stabilizing growth hormone receptors in enterocytes and enhancing cellular repair mechanisms.
- Protects and heals the gut mucosa, likely by stabilizing growth hormone receptors in enterocytes and enhancing cellular repair mechanisms.
- Anti-Inflammatory Action
- Downregulates pro-inflammatory cytokines (like TNF-α and IL-6) while upregulating anti-inflammatory responses.
Primary Benefits
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Tendon and Ligament Healing
- Accelerates recovery from strains, sprains, and tears.
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Increases collagen synthesis and tendon cell migration.
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Muscle and Nerve Regeneration
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Enhances muscle fiber regeneration post-injury.
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Supports nerve healing and reduces neuropathic pain.
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Gut Protection and Healing
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Repairs stomach lining and intestinal barrier.
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May improve symptoms of IBS, gastritis, colitis, or leaky gut.
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Joint and Bone Health
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Improves joint integrity and reduces inflammation.
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Can assist in cartilage repair.
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Anti-Inflammatory and Cytoprotective
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Reduces systemic inflammation markers.
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Protects organs under oxidative stress (e.g., liver, heart, brain).
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Potential Brain Protection
- Crosses the blood-brain barrier.
- May help protect neurons from oxidative or inflammatory damage.
Suggested Dosage (Capsule Form)
Note: Always consult a qualified healthcare provider before use. BPC-157 is not FDA-approved for medical use.
Common capsule dosages:
- 250 mcg to 500 mcg per capsule
- Typical oral regimen:
- 250–500 mcg 1–2 times daily, depending on severity of symptoms or goals.
- Cycle Length: 4–8 weeks, followed by a break.
Timing:
- Best taken on an empty stomach or 30 minutes before meals for improved absorption.
- If gut healing is the goal, take in the morning before food.
⚠️ Safety and Side Effects
BPC-157 is generally well tolerated, but since it’s not approved as a drug, long-term human safety data is limited.
Possible mild side effects (rare):
- Temporary nausea or digestive upset
- Light headache or dizziness
- Mild fatigue or changes in appetite
Do NOT use if:
- Pregnant or breastfeeding
- You have an active cancer (due to angiogenesis stimulation)
- You’re allergic to peptide ingredients or capsule fillers
Key Features (For Research Purposes)
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Serving Size: 1 Capsule
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Servings Per Container: 60
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Amount Per Serving: 250 mcg
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Other Ingredients: Gelatin (Capsules), Rice Flour, Silicon Dioxide, Magnesium Stearate
